XDemics
is Fundamentally Improving The WayCells Are Grown

Slashing timelines  and costs

Vastly accelerating biomedical innovation

From the lab bench to industrial-scale production

Learn more

Our Patented Technology:
High Density Cell Respiration™

$2b cultureware market 20251

AT THE LAB BENCH

Its influence soars from gaining a better understanding of the building blocks of life to breakthrough innovations in therapeutics, including cutting-edge cell & gene therapies, ultimately reducing their production costs by 80-90%.

  • 95% reduced hands-on time

  • 25X improvement in productivity

  • Significant reduction in space

Applications:
Early hit to lead production
Target production
High throughput screening
Cell based assays
Protein engineering & design
Immunology studies
CRISPR / gene editing
Proteomics
Genomics
Metabolomics
Early hit to lead production
1 Expansify™ plate equals 25 standard Petri dishes
$9.5b C&GT manufacturing services market 20252

IN THE PRODUCTION FACILITY

HDCR™ enables unprecedented quality,
yields, and efficiency. Our technology drives
innovation, streamlines workflows, and
dramatically reduces costs across biomedical R&D.

  • 80% cost decrease of cell and gene therapies

  • Achieves cost-parity with biologics

  • Making life-changing treatments accessible

Applications:
Gene therapy production
T-cell production
Stem cell production
Biologics production
Process development
TIL therapy expansion
Oncolytic virus production
Regenerative medicine
Exosome production
Gene therapy production
5-Liter Profusion-Midi ™ replaces 250-Liter vessel
1. Research and Markets (Feb 2025)
2. TBRC Report (Jan 2025)

Addressing a
Key Bottleneck

Poor oxygen transfer is a major bottleneck in cell growth at all scales, limiting yield, quality, efficiency, and reproducibility. XDemics overcomes this challenge by ensuring optimal oxygenation, enabling cells to reliably thrive at densities 10-100X higher than traditional methods

Polystyrene
dishes, T-flasks
Standard
bioreactors
10–100X
XDemics
Tissue
Mammalianmillion cells / mL
kLa Oxygen (1 / hr)
~ 1
0.8
~ 10
8
~ 100 – 1000
60
~ 100 – 1000
80
How it works

XDemics’ innovation combines a gas-permeable membrane with an exclusive geometric design to create ideal replicative niches for cells to grow. This unique system ensures high-density cell growth while maintaining quality, scalability, and efficiency across research and industrial applications.

A Smarter Way to Grow Cells

Conventional polystyrene Petri dish or T-flask

Expansify™ plate or tray

Two-dimensional growth to confluent monolayer
Two-dimensional growth to confluent monolayer
0.25M cells / 24-well plate
Three-dimensional growth of thriving cells
Three-dimensional growth of thriving cells
8M cells / 24-well plate
demonstration

Massive expansion of human cells

50,000 K-562 cells were seeded at Day 0, cells were expanded over 9 days in an Expansify™24-well plate. 9 million cells were harvested at >95% viability.

Day 1

Day 2

Day 3

50,000
250,000
8,000,000
Initial Seeded Cells (Day 0)
Conventional Plate Limit
Breakthrough Cell Growth (Day 7)
Graph scaled for readability—actual cell expansion is 32X over 7 days, far exceeding conventional limits.

Revolutionizing Cell Growth–Scaling Beyond Limits

Traditional cell culture methods are limited in scale and efficiency. With our breakthrough technology, we’ve expanded cell growth capabilities far beyond conventional limits. This graph illustrates the massive difference in viable cell yield over just 7 days in a single well of a 24-well plate.

True scalability

Identical geometry and environment from a 24-well plate to 50L bioreactor

Stackable membrane sheets with media + gas flow

Precise & linear scaleup creates streamlined, simplified
process optimization with decreased risk, improved quality & control

True Scalability

Identical geometry and environment from a 24-well plate to 50L bioreactor

Precise & linear scaleup creates streamlined, simplified process optimization with decreased risk, improved quality & control.

Contact us

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